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Different measures of “genome-wide” DNA methylation exhibit unique properties in placental and somatic tissues

DNA methylation of CpGs located in two types of repetitive elements—LINE1 (L1) and Alu—is used to assess “global” changes in DNA methylation in studies of human disease and environmental exposure. L1 and Alu contribute close to 30% of all base pairs in the human genome and transposition of repetitiv...

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Autori principali: Price, E. Magda, Cotton, Allison M., Peñaherrera, Maria S., McFadden, Deborah E., Kobor, Michael S., Robinson, Wendy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398992/
https://ncbi.nlm.nih.gov/pubmed/22531475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.20221
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