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Different measures of “genome-wide” DNA methylation exhibit unique properties in placental and somatic tissues

DNA methylation of CpGs located in two types of repetitive elements—LINE1 (L1) and Alu—is used to assess “global” changes in DNA methylation in studies of human disease and environmental exposure. L1 and Alu contribute close to 30% of all base pairs in the human genome and transposition of repetitiv...

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Hlavní autoři: Price, E. Magda, Cotton, Allison M., Peñaherrera, Maria S., McFadden, Deborah E., Kobor, Michael S., Robinson, Wendy
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398992/
https://ncbi.nlm.nih.gov/pubmed/22531475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.20221
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