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Profiling placental and fetal DNA methylation in human neural tube defects

BACKGROUND: The incidence of neural tube defects (NTDs) declined by about 40 % in Canada with the introduction of a national folic acid (FA) fortification program. Despite the fact that few Canadians currently exhibit folate deficiency, NTDs are still the second most common congenital abnormality. F...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Price, E. Magda, Peñaherrera, Maria S., Portales-Casamar, Elodie, Pavlidis, Paul, Van Allen, Margot I., McFadden, Deborah E., Robinson, Wendy P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756451/
https://ncbi.nlm.nih.gov/pubmed/26889207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0054-8
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