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Combination of Sulindac and Dichloroacetate Kills Cancer Cells via Oxidative Damage
Sulindac is an FDA-approved non-steroidal anti-inflammatory drug with documented anticancer activities. Our recent studies showed that sulindac selectively enhanced the killing of cancer cells exposed to oxidizing agents via production of reactive oxygen species (ROS) resulting in mitochondrial dysf...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3398923/ https://ncbi.nlm.nih.gov/pubmed/22866174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039949 |
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