Mesenchymal Stromal Cells but Not Cardiac Fibroblasts Exert Beneficial Systemic Immunomodulatory Effects in Experimental Myocarditis

Systemic application of mesenchymal stromal cells (MSCs) in inflammatory cardiomyopathy exerts cardiobeneficial effects. The mode of action is unclear since a sufficient and long-acting cardiac homing of MSCs is unlikely. We therefore investigated the regulation of the immune response in coxsackievi...

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Main Authors: Savvatis, Konstantinos, van Linthout, Sophie, Miteva, Kapka, Pappritz, Kathleen, Westermann, Dirk, Schefold, Joerg C., Fusch, Gerhard, Weithäuser, Alice, Rauch, Ursula, Becher, Peter-Moritz, Klingel, Karin, Ringe, Jochen, Kurtz, Andreas, Schultheiss, Heinz-Peter, Tschöpe, Carsten
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398879/
https://ncbi.nlm.nih.gov/pubmed/22815907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041047
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