Mesenchymal Stromal Cells but Not Cardiac Fibroblasts Exert Beneficial Systemic Immunomodulatory Effects in Experimental Myocarditis

Systemic application of mesenchymal stromal cells (MSCs) in inflammatory cardiomyopathy exerts cardiobeneficial effects. The mode of action is unclear since a sufficient and long-acting cardiac homing of MSCs is unlikely. We therefore investigated the regulation of the immune response in coxsackievi...

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Auteurs principaux: Savvatis, Konstantinos, van Linthout, Sophie, Miteva, Kapka, Pappritz, Kathleen, Westermann, Dirk, Schefold, Joerg C., Fusch, Gerhard, Weithäuser, Alice, Rauch, Ursula, Becher, Peter-Moritz, Klingel, Karin, Ringe, Jochen, Kurtz, Andreas, Schultheiss, Heinz-Peter, Tschöpe, Carsten
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398879/
https://ncbi.nlm.nih.gov/pubmed/22815907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041047
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