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Cellular and molecular mechanisms of metformin: an overview

Considerable efforts have been made since the 1950s to better understand the cellular and molecular mechanisms of action of metformin, a potent antihyperglycemic agent now recommended as the first line oral therapy for type 2 diabetes (T2D). The main effect of this drug from the biguanide family is...

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Detalhes bibliográficos
Main Authors: Viollet, Benoit, Guigas, Bruno, Sanz Garcia, Nieves, Leclerc, Jocelyne, Foretz, Marc, Andreelli, Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press on behalf of the Medical Research Society and the Biochemical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398862/
https://ncbi.nlm.nih.gov/pubmed/22117616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20110386
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