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AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside

AICA riboside (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) has been extensively used in cells to activate the AMPK (AMP-activated protein kinase), a metabolic sensor involved in cell energy homoeostasis. In the present study, we investigated the effects of AICA riboside on mitochondrial oxi...

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Detalhes bibliográficos
Main Authors: Guigas, Bruno, Taleux, Nellie, Foretz, Marc, Detaille, Dominique, Andreelli, Fabrizio, Viollet, Benoit, Hue, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896274/
https://ncbi.nlm.nih.gov/pubmed/17324122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070105
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