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miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia

High BAALC expression levels are associated with poor outcome in cytogenetically normal acute myeloid leukemia (CN-AML) patients. Recently, miR-3151 was discovered in intron 1 of BAALC. To evaluate the prognostic significance of miR-3151 expression levels and to gain insight into the biologic and pr...

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Detalhes bibliográficos
Main Authors: Eisfeld, Ann-Kathrin, Marcucci, Guido, Maharry, Kati, Schwind, Sebastian, Radmacher, Michael D., Nicolet, Deedra, Becker, Heiko, Mrózek, Krzysztof, Whitman, Susan P., Metzeler, Klaus H., Mendler, Jason H., Wu, Yue-Zhong, Liyanarachchi, Sandya, Patel, Ravi, Baer, Maria R., Powell, Bayard L., Carter, Thomas H., Moore, Joseph O., Kolitz, Jonathan E., Wetzler, Meir, Caligiuri, Michael A., Larson, Richard A., Tanner, Stephan M., de la Chapelle, Albert, Bloomfield, Clara D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398762/
https://ncbi.nlm.nih.gov/pubmed/22529287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-408492
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