miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia

High BAALC expression levels are associated with poor outcome in cytogenetically normal acute myeloid leukemia (CN-AML) patients. Recently, miR-3151 was discovered in intron 1 of BAALC. To evaluate the prognostic significance of miR-3151 expression levels and to gain insight into the biologic and pr...

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Autori principali: Eisfeld, Ann-Kathrin, Marcucci, Guido, Maharry, Kati, Schwind, Sebastian, Radmacher, Michael D., Nicolet, Deedra, Becker, Heiko, Mrózek, Krzysztof, Whitman, Susan P., Metzeler, Klaus H., Mendler, Jason H., Wu, Yue-Zhong, Liyanarachchi, Sandya, Patel, Ravi, Baer, Maria R., Powell, Bayard L., Carter, Thomas H., Moore, Joseph O., Kolitz, Jonathan E., Wetzler, Meir, Caligiuri, Michael A., Larson, Richard A., Tanner, Stephan M., de la Chapelle, Albert, Bloomfield, Clara D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
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Plenary Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398762/
https://ncbi.nlm.nih.gov/pubmed/22529287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-408492
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