N-Acetylcysteine Normalizes Glutamate Levels in Cocaine-Dependent Patients: A Randomized Crossover Magnetic Resonance Spectroscopy Study

Treatment with N-acetylcysteine (NAC) normalizes glutamate (Glu) homeostasis and prevents relapse in drug-dependent animals. However, the effect of NAC on brain Glu levels in substance-dependent humans has not yet been investigated. Proton magnetic resonance spectroscopy ((1)H MRS) was used to inves...

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Main Authors: Schmaal, Lianne, Veltman, Dick J, Nederveen, Aart, van den Brink, Wim, Goudriaan, Anna E
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398721/
https://ncbi.nlm.nih.gov/pubmed/22549117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.66
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