A Common Variant in ERBB4 Regulates GABA Concentrations in Human Cerebrospinal Fluid

The neuregulin 1 (NRG1) receptor ErbB4 is involved in the development of cortical inhibitory GABAergic circuits and NRG1-ErbB4 signaling has been implicated in schizophrenia (SCZ). A magnetic resonance spectroscopy ((1)H-MRS) study has demonstrated that a single-nucleotide polymorphism in ERBB4, rs7...

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Autors principals: Luykx, Jurjen J, Vinkers, Christiaan H, Bakker, Steven C, Visser, Wouter F, van Boxmeer, Loes, Strengman, Eric, van Eijk, Kristel R, Lens, Judith A, Borgdorff, Paul, Keijzers, Peter, Kappen, Teus H, van Dongen, Eric P A, Bruins, Peter, Verhoeven, Nanda M, de Koning, Tom J, Kahn, René S, Ophoff, Roel A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398713/
https://ncbi.nlm.nih.gov/pubmed/22549119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.57
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