Identification of schizophrenia-associated loci by combining DNA methylation and gene expression data from whole blood

Emerging evidence suggests that schizophrenia (SZ) susceptibility involves variation at genetic, epigenetic and transcriptome levels. We describe an integrated approach that leverages DNA methylation and gene expression data to prioritize genetic variation involved in disease. DNA methylation levels...

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Bibliografske podrobnosti
izdano v:Eur J Hum Genet
Main Authors: van Eijk, Kristel R, de Jong, Simone, Strengman, Eric, Buizer-Voskamp, Jacobine E, Kahn, René S, Boks, Marco P, Horvath, Steve, Ophoff, Roel A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795100/
https://ncbi.nlm.nih.gov/pubmed/25424713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.245
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