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Designed Ankyrin Repeat Proteins as Scaffolds for Multivalent Recognition

Ankyrin repeat (AR) proteins are composed of tandem repeats of a basic structural motif of ca. 33 amino acid residues that form a β-turn followed by two antiparallel α-helices. Multiple repeats stack together in a modular fashion to form a scaffold that is ideally suited for the presentation of mult...

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Bibliographische Detailangaben
Hauptverfasser: Hollenbeck, Jessica J., Danner, Derek J., Landgren, Rachel M., Rainbolt, Thomas K., Roberts, Danielle S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398510/
https://ncbi.nlm.nih.gov/pubmed/22681396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300455f
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