A varicella-zoster virus mutant impaired for latency in rodents, but not impaired for replication in cell culture

While trying to generate a site-directed deletion in the ORF63 latency-associated gene of varicella-zoster virus (VZV) Oka, we constructed a virus with an unexpected rearrangement. The virus has a small deletion in both copies of ORF63 and insertion of a cassette between ORFs64 and 65 containing (a)...

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Hlavní autoři: Ambagala, Aruna P.N., Krogmann, Tammy, Qin, Jing, Pesnicak, Lesley, Cohen, Jeffrey I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398405/
https://ncbi.nlm.nih.gov/pubmed/20116820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.01.007
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