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A varicella-zoster virus mutant impaired for latency in rodents, but not impaired for replication in cell culture
While trying to generate a site-directed deletion in the ORF63 latency-associated gene of varicella-zoster virus (VZV) Oka, we constructed a virus with an unexpected rearrangement. The virus has a small deletion in both copies of ORF63 and insertion of a cassette between ORFs64 and 65 containing (a)...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3398405/ https://ncbi.nlm.nih.gov/pubmed/20116820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.01.007 |
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