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The C5 Convertase Is Not Required for Activation of the Terminal Complement Pathway in Murine Experimental Cerebral Malaria

Cerebral malaria (CM) is the most severe manifestation of clinical malaria syndromes and has a high fatality rate especially in the developing world. Recent studies demonstrated that C5(−/−) mice are resistant to experimental CM (ECM) and that protection was due to the inability to form the membrane...

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Bibliografische gegevens
Hoofdauteurs: Ramos, Theresa N., Darley, Meghan M., Weckbach, Sebastian, Stahel, Philip F., Tomlinson, Stephen, Barnum, Scott R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397900/
https://ncbi.nlm.nih.gov/pubmed/22689574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.378364
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