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The Membrane Attack Complex of Complement is Required for the Development of Murine Experimental Cerebral Malaria

Cerebral malaria (CM) is the most severe complication of Plasmodium falciparum infection and accounts for a large number of malaria fatalities worldwide. Recent studies demonstrated that C5(−/−) mice are resistant to experimental CM (ECM) and suggested that protection was due to loss of C5a-induced...

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Detalhes bibliográficos
Main Authors: Ramos, Theresa N., Darley, Meghan M., Hu, Xianzhen, Billker, Oliver, Rayner, Julian C., Ahras, Malika, Wohler, Jillian E., Barnum, Scott R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110530/
https://ncbi.nlm.nih.gov/pubmed/21572031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100603
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