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The Epac-Rap1 Signaling Pathway Controls cAMP-mediated Exocytosis of Weibel-Palade Bodies in Endothelial Cells

Endothelial cells contain specialized storage organelles called Weibel-Palade bodies (WPBs) that release their content into the vascular lumen in response to specific agonists that raise intracellular Ca(2+) or cAMP. We have previously shown that cAMP-mediated WPB release is dependent on protein kin...

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Detalhes bibliográficos
Main Authors: van Hooren, Kathinka W. E. M., van Agtmaal, Ellen L., Fernandez-Borja, Mar, van Mourik, Jan A., Voorberg, Jan, Bierings, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397898/
https://ncbi.nlm.nih.gov/pubmed/22511766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.321976
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