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Critical Determinants of Human α-Defensin 5 Activity against Non-enveloped Viruses
Human α-defensins, such as human α-defensin 5 (HD5), block infection of non-enveloped viruses, including human adenoviruses (AdV), papillomaviruses (HPV), and polyomaviruses. Through mutational analysis of HD5, we have identified arginine residues that contribute to antiviral activity against AdV an...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397880/ https://ncbi.nlm.nih.gov/pubmed/22637473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.354068 |
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