Ezrin-anchored Protein Kinase A Coordinates Phosphorylation-dependent Disassembly of a NHERF1 Ternary Complex to Regulate Hormone-sensitive Phosphate Transport

Congenital defects in the Na/H exchanger regulatory factor-1 (NHERF1) are linked to disordered phosphate homeostasis and skeletal abnormalities in humans. In the kidney, these mutations interrupt parathyroid hormone (PTH)-responsive sequestration of the renal phosphate transporter, Npt2a, with ensui...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Bin, Means, Chris K., Yang, Yanmei, Mamonova, Tatyana, Bisello, Alessandro, Altschuler, Daniel L., Scott, John D., Friedman, Peter A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397842/
https://ncbi.nlm.nih.gov/pubmed/22628548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.369405
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