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Noncanonical Sequences Involving NHERF1 Interaction with NPT2A Govern Hormone-Regulated Phosphate Transport: Binding Outside the Box

Na(+)/H(+) exchange factor-1 (NHERF1), a multidomain PDZ scaffolding phosphoprotein, is required for the type II sodium-dependent phosphate cotransporter (NPT2A)-mediated renal phosphate absorption. Both PDZ1 and PDZ2 domains are involved in NPT2A-dependent phosphate uptake. Though harboring identic...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mamonova, Tatyana, Friedman, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866199/
https://ncbi.nlm.nih.gov/pubmed/33499384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22031087
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