Leukemia Inhibitory Factor Coordinates the Down-regulation of the Visual Cycle in the Retina and Retinal-pigmented Epithelium

Leukemia inhibitory factor (LIF), an interleukin-6 family neurocytokine, is up-regulated in response to different types of retinal stress and has neuroprotective activity through activation of the gp130 receptor/STAT3 pathway. We observed that LIF induces rapid, robust, and sustained activation of S...

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Hlavní autoři: Chucair-Elliott, Ana J., Elliott, Michael H., Wang, Jiangang, Moiseyev, Gennadiy P., Ma, Jian-Xing, Politi, Luis E., Rotstein, Nora P., Akira, Shizuo, Uematsu, Satoshi, Ash, John D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397836/
https://ncbi.nlm.nih.gov/pubmed/22645143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378240
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