By-Passing Large Screening Experiments Using Sequencing as a Tool to Identify scFv Fragments Targeting Atherosclerotic Lesions in a Novel In Vivo Phage Display Selection

Atherosclerosis is a chronic, progressive inflammatory disease that may develop into vulnerable lesions leading to thrombosis. To interrogate the molecular components involved in this process, single-chain variable fragments (scFvs) from a semi-synthetic human antibody library were selected on the l...

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Main Authors: Deramchia, Kamel, Jacobin-Valat, Marie-Josee, Laroche-Traineau, Jeanny, Bonetto, Stephane, Sanchez, Stephane, Dos Santos, Pierre, Massot, Philippe, Franconi, Jean-Michel, Martineau, Pierre, Clofent-Sanchez, Gisele
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397503/
https://ncbi.nlm.nih.gov/pubmed/22837671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13066902
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