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Chalinulasterol, a Chlorinated Steroid Disulfate from the Caribbean Sponge Chalinula molitba. Evaluation of Its Role as PXR Receptor Modulator

Chalinulasterol (1) a new chlorinated sterol disulfate was isolated from the Caribbean sponge Chalinula molitba. Its structure was elucidated using mass spectrometry and NMR experiments. The possible role of chalinulasterol as modulator of the PXR nuclear receptor was investigated but, in spite of t...

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Detalhes bibliográficos
Main Authors: Teta, Roberta, Sala, Gerardo Della, Renga, Barbara, Mangoni, Alfonso, Fiorucci, Stefano, Costantino, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397446/
https://ncbi.nlm.nih.gov/pubmed/22822379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10061383
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