Smenamides A and B, Chlorinated Peptide/Polyketide Hybrids Containing a Dolapyrrolidinone Unit from the Caribbean Sponge Smenospongia aurea. Evaluation of Their Role as Leads in Antitumor Drug Research

An in-depth study of the secondary metabolites contained in the Caribbean sponge Smenospongia aurea led to the isolation of smenamide A (1) and B (2), hybrid peptide/polyketide compounds containing a dolapyrrolidinone unit. Their structures were elucidated using high-resolution ESI-MS/MS and homo- a...

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Main Authors: Teta, Roberta, Irollo, Elena, Della Sala, Gerardo, Pirozzi, Giuseppe, Mangoni, Alfonso, Costantino, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853738/
https://ncbi.nlm.nih.gov/pubmed/24217287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md11114451
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