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Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein

Coronaviruses are enveloped positive-stranded RNA viruses that replicate in the cytoplasm. To deliver their nucleocapsid into the host cell, they rely on the fusion of their envelope with the host cell membrane. The spike glycoprotein (S) mediates virus entry and is a primary determinant of cell tro...

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Autori principali: Belouzard, Sandrine, Millet, Jean K., Licitra, Beth N., Whittaker, Gary R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397359/
https://ncbi.nlm.nih.gov/pubmed/22816037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v4061011
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