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Presence of Multiple Independent Effects in Risk Loci of Common Complex Human Diseases

Many genetic loci and SNPs associated with many common complex human diseases and traits are now identified. The total genetic variance explained by these loci for a trait or disease, however, has often been very small. Much of the “missing heritability” has been revealed to be hidden in the genome...

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Bibliografiske detaljer
Hovedforfatter: Ke, Xiayi
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397258/
https://ncbi.nlm.nih.gov/pubmed/22770979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.05.020
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