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Association Analysis of the Extended MHC Region in Celiac Disease Implicates Multiple Independent Susceptibility Loci
Celiac disease is a common autoimmune disease caused by sensitivity to the dietary protein gluten. Forty loci have been implicated in the disease. All disease loci have been characterized as low-penetrance, with the exception of the high-risk genotypes in the HLA-DQA1 and HLA-DQB1 genes, which are n...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355177/ https://ncbi.nlm.nih.gov/pubmed/22615847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036926 |
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