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Open Sesame: activating dormant replication origins in the mouse immunoglobulin heavy chain (Igh) locus

Chromosomal DNA replication in mammals initiates from replication origins whose activity differs in accordance with cell type and differentiation state. In addition to origins that are active in unperturbed conditions, chromosomes also contain dormant origins that can become functional in response t...

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Detalhes bibliográficos
Main Authors: Borowiec, James A., Schildkraut, Carl L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397252/
https://ncbi.nlm.nih.gov/pubmed/21571518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2011.04.004
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