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Open Sesame: activating dormant replication origins in the mouse immunoglobulin heavy chain (Igh) locus

Chromosomal DNA replication in mammals initiates from replication origins whose activity differs in accordance with cell type and differentiation state. In addition to origins that are active in unperturbed conditions, chromosomes also contain dormant origins that can become functional in response t...

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Библиографические подробности
Главные авторы: Borowiec, James A., Schildkraut, Carl L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397252/
https://ncbi.nlm.nih.gov/pubmed/21571518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2011.04.004
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