Regulation of DNA Replication within the Immunoglobulin Heavy-Chain Locus During B Cell Commitment

The temporal order of replication of mammalian chromosomes appears to be linked to their functional organization, but the process that establishes and modifies this order during cell differentiation remains largely unknown. Here, we studied how the replication of the Igh locus initiates, progresses,...

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Main Authors: Demczuk, Agnieszka, Gauthier, Michel G., Veras, Ingrid, Kosiyatrakul, Settapong, Schildkraut, Carl L., Busslinger, Meinrad, Bechhoefer, John, Norio, Paolo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393677/
https://ncbi.nlm.nih.gov/pubmed/22807655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001360
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