Regulation of DNA Replication within the Immunoglobulin Heavy-Chain Locus During B Cell Commitment

The temporal order of replication of mammalian chromosomes appears to be linked to their functional organization, but the process that establishes and modifies this order during cell differentiation remains largely unknown. Here, we studied how the replication of the Igh locus initiates, progresses,...

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Main Authors: Demczuk, Agnieszka, Gauthier, Michel G., Veras, Ingrid, Kosiyatrakul, Settapong, Schildkraut, Carl L., Busslinger, Meinrad, Bechhoefer, John, Norio, Paolo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393677/
https://ncbi.nlm.nih.gov/pubmed/22807655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001360
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