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Discrete Bimodal Probes for Thrombus Imaging
Here we report a generalizable solid/solution phase strategy for the synthesis of discrete bimodal fibrin-targeted imaging probes. A fibrin-specific peptide was conjugated with two distinct imaging reporters at the C- and N-terminus. In vitro studies demonstrated retention of fibrin affinity and spe...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397236/ https://ncbi.nlm.nih.gov/pubmed/22698259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3045635 |
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