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Discrete Bimodal Probes for Thrombus Imaging

Here we report a generalizable solid/solution phase strategy for the synthesis of discrete bimodal fibrin-targeted imaging probes. A fibrin-specific peptide was conjugated with two distinct imaging reporters at the C- and N-terminus. In vitro studies demonstrated retention of fibrin affinity and spe...

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Bibliografiske detaljer
Main Authors: Uppal, Ritika, Ciesienski, Kate L., Chonde, Daniel B., Loving, Galen S., Caravan, Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397236/
https://ncbi.nlm.nih.gov/pubmed/22698259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3045635
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