Podocyte vascular endothelial growth factor (Vegf(164)) overexpression causes severe nodular glomerulosclerosis in a mouse model of type 1 diabetes

AIMS/HYPOTHESIS: The pathogenic role of excessive vascular endothelial growth factor (VEGF)-A in diabetic nephropathy has not been defined. We sought to test whether increased podocyte VEGF-A signalling determines the severity of diabetic glomerulopathy. METHODS: Podocyte-specific, doxycycline-induc...

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Main Authors: Veron, D., Bertuccio, C. A., Marlier, A., Reidy, K., Garcia, A. M., Jimenez, J., Velazquez, H., Kashgarian, M., Moeckel, G. W., Tufro, A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397150/
https://ncbi.nlm.nih.gov/pubmed/21318407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-2034-z
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