Live-Cell Imaging of Single Receptor Composition Using Zero-Mode Waveguide Nanostructures

We exploit the optical and spatial features of sub-wavelength nanostructures to examine individual receptors on the plasma membrane of living cells. Receptors were sequestered in portions of the membrane projected into zero-mode waveguides (ZMWs). Using single-step photobleaching of GFP incorporated...

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Main Authors: Richards, Christopher I., Luong, Khai, Srinivasan, Rahul, Turner, Stephen W., Dougherty, Dennis A., Korlach, Jonas, Lester, Henry A.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397148/
https://ncbi.nlm.nih.gov/pubmed/22668081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl301480h
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