Comparison of the effect of the GABA(B) receptor agonist, baclofen, and the positive allosteric modulator of the GABA(B) receptor, GS39783, on alcohol self-administration in three different lines of alcohol-preferring rats

BACKGROUND: Administration of the GABA(B) receptor agonist, baclofen, and positive allosteric modulator (PAM), GS39783, has been repeatedly reported to suppress multiple alcohol-related behaviors, including operant oral alcohol self-administration, in rats. The present study was designed to compare...

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Main Authors: Maccioni, Paola, Zaru, Alessandro, Loi, Barbara, Lobina, Carla, Carai, Mauro A.M., Gessa, Gian Luigi, Capra, Alessandro, Mugnaini, Claudia, Pasquini, Serena, Corelli, Federico, Hyytiä, Petri, Lumeng, Lawrence, Colombo, Giancarlo
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396797/
https://ncbi.nlm.nih.gov/pubmed/22486245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2012.01782.x
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