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ALK+ Anaplastic Large Cell Lymphoma Exhibits Phosphatidylinositol-3 Kinase/Akt Activity with Retained but Inactivated PTEN – A Report from the Children’s Oncology Group

BACKGROUND: ALK+ Anaplastic Large Cell Lymphoma (ALCL) is usually a disease of young patients. We investigated phosphatidylinositol-3 kinase (PI3K)/Akt pathway-associated factors in pediatric cases and cell lines. PROCEDURE: Patient materials consisted of tissue slides of ALK+/CD30+ ALCL from 33 pat...

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Detalhes bibliográficos
Main Authors: Thakral, Charu, Hutchison, Robert E., Shrimpton, Antony, Barrett, Donna, Laver, Joseph, Link, Michael, Halleran, Devin R., Hudson, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396737/
https://ncbi.nlm.nih.gov/pubmed/22488797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24153
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