Ubiquitin-proteasome-rich cytoplasmic structures in neutrophils of patients with Shwachman-Diamond syndrome

BACKGROUND: Shwachman–Diamond syndrome is an autosomal recessive disorder in which severe bone marrow dysfunction causes neutropenia and an increased risk of leukemia. Recently, novel particulate cytoplasmic structures, rich in ubiquitinated and proteasomal proteins, have been detected in epithelial...

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Autors principals: Necchi, Vittorio, Minelli, Antonella, Sommi, Patrizia, Vitali, Agostina, Caruso, Roberta, Longoni, Daniela, Frau, Maria Rita, Nasi, Cristina, De Gregorio, Fabiola, Zecca, Marco, Ricci, Vittorio, Danesino, Cesare, Solcia, Enrico
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2012
Matèries:
Original Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396678/
https://ncbi.nlm.nih.gov/pubmed/22271888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.048462
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