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Genetic modifiers of β-thalassemia and clinical severity as assessed by age at first transfusion

BACKGROUND: The clinical and hematologic features of β-thalassemia are modulated by different factors, resulting in a wide range of clinical severity. The main factors are the type of disease-causing mutation and the ability to produce α-globin and γ-globin chains. In the present study we investigat...

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Bibliografiset tiedot
Päätekijät: Danjou, Fabrice, Anni, Franco, Perseu, Lucia, Satta, Stefania, Dessì, Carlo, Lai, Maria Eliana, Fortina, Paolo, Devoto, Marcella, Galanello, Renzo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ferrata Storti Foundation 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396667/
https://ncbi.nlm.nih.gov/pubmed/22271886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.053504
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