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Genetic modifiers of β-thalassemia and clinical severity as assessed by age at first transfusion
BACKGROUND: The clinical and hematologic features of β-thalassemia are modulated by different factors, resulting in a wide range of clinical severity. The main factors are the type of disease-causing mutation and the ability to produce α-globin and γ-globin chains. In the present study we investigat...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396667/ https://ncbi.nlm.nih.gov/pubmed/22271886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.053504 |
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