GM-CSF Priming Drives Bone Marrow-Derived Macrophages to a Pro-Inflammatory Pattern and Downmodulates PGE(2) in Response to TLR2 Ligands

In response to pathogen recognition by Toll-like receptors (TLRs) on their cell surface, macrophages release lipid mediators and cytokines that are widely distributed throughout the body and play essential roles in host responses. Granulocyte macrophage colony-stimulating factor (GM-CSF) is importan...

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Hauptverfasser: Sorgi, Carlos Arterio, Rose, Stephanie, Court, Nathalie, Carlos, Daniela, Paula-Silva, Francisco Wanderley Garcia, Assis, Patricia Aparecida, Frantz, Fabiani Gai, Ryffel, Bernhard, Quesniaux, Valerie, Faccioli, Lúcia Helena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396658/
https://ncbi.nlm.nih.gov/pubmed/22808181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040523
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