Acute Podocyte Vascular Endothelial Growth Factor (VEGF-A) Knockdown Disrupts alpha(V)beta(3) Integrin Signaling in the Glomerulus

Podocyte or endothelial cell VEGF-A knockout causes thrombotic microangiopathy in adult mice. To study the mechanism involved in acute and local injury caused by low podocyte VEGF-A we developed an inducible, podocyte-specific VEGF-A knockdown mouse, and we generated an immortalized podocyte cell li...

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Autors principals: Veron, Delma, Villegas, Guillermo, Aggarwal, Pardeep Kumar, Bertuccio, Claudia, Jimenez, Juan, Velazquez, Heino, Reidy, Kimberly, Abrahamson, Dale R., Moeckel, Gilbert, Kashgarian, Michael, Tufro, Alda
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396653/
https://ncbi.nlm.nih.gov/pubmed/22808199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040589
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