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Transgenic Anopheles stephensi coexpressing single-chain antibodies resist Plasmodium falciparum development
Anopheles stephensi mosquitoes expressing m1C3, m4B7, or m2A10 single-chain antibodies (scFvs) have significantly lower levels of infection compared to controls when challenged with Plasmodium falciparum, a human malaria pathogen. These scFvs are derived from antibodies specific to a parasite chitin...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396534/ https://ncbi.nlm.nih.gov/pubmed/22689959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207738109 |
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