Conditional ablation of CD205(+) conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo

Dendritic cells (DCs) are composed of multiple subsets that play a dual role in inducing immunity and tolerance. However, it is unclear how CD205(+) conventional DCs (cDCs) control immune responses in vivo. Here we generated knock-in mice with the selective conditional ablation of CD205(+) cDCs. CD2...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Fukaya, Tomohiro, Murakami, Ryuichi, Takagi, Hideaki, Sato, Kaori, Sato, Yumiko, Otsuka, Haruna, Ohno, Michiko, Hijikata, Atsushi, Ohara, Osamu, Hikida, Masaki, Malissen, Bernard, Sato, Katsuaki
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396526/
https://ncbi.nlm.nih.gov/pubmed/22736794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202208109
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