Polyene antibiotic that inhibits membrane transport proteins

The limited therapeutic arsenal and the increase in reports of fungal resistance to multiple antifungal agents have made fungal infections a major therapeutic challenge. The polyene antibiotics are the only group of antifungal antibiotics that directly target the plasma membrane via a specific inter...

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Bibliographic Details
Main Authors: te Welscher, Yvonne Maria, van Leeuwen, Martin Richard, de Kruijff, Ben, Dijksterhuis, Jan, Breukink, Eefjan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396478/
https://ncbi.nlm.nih.gov/pubmed/22733749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203375109
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