p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

On the basis mainly of pharmacological experiments, the p38α MAP kinase isoform has been established as an important regulator of immune and inflammatory responses. However, the role of the related p38γ and p38δ kinases has remained unclear. Here, we show that deletion of p38γ and p38δ impaired the...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Risco, Ana, del Fresno, Carlos, Mambol, Agnes, Alsina-Beauchamp, Dayanira, MacKenzie, Kirsty F., Yang, Huei-Ting, Barber, Domingo F., Morcelle, Carmen, Arthur, J. Simon C., Ley, Steven C., Ardavin, Carlos, Cuenda, Ana
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396476/
https://ncbi.nlm.nih.gov/pubmed/22733747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207290109
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki