p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

On the basis mainly of pharmacological experiments, the p38α MAP kinase isoform has been established as an important regulator of immune and inflammatory responses. However, the role of the related p38γ and p38δ kinases has remained unclear. Here, we show that deletion of p38γ and p38δ impaired the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Risco, Ana, del Fresno, Carlos, Mambol, Agnes, Alsina-Beauchamp, Dayanira, MacKenzie, Kirsty F., Yang, Huei-Ting, Barber, Domingo F., Morcelle, Carmen, Arthur, J. Simon C., Ley, Steven C., Ardavin, Carlos, Cuenda, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396476/
https://ncbi.nlm.nih.gov/pubmed/22733747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207290109
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados