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p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

On the basis mainly of pharmacological experiments, the p38α MAP kinase isoform has been established as an important regulator of immune and inflammatory responses. However, the role of the related p38γ and p38δ kinases has remained unclear. Here, we show that deletion of p38γ and p38δ impaired the...

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書誌詳細
主要な著者: Risco, Ana, del Fresno, Carlos, Mambol, Agnes, Alsina-Beauchamp, Dayanira, MacKenzie, Kirsty F., Yang, Huei-Ting, Barber, Domingo F., Morcelle, Carmen, Arthur, J. Simon C., Ley, Steven C., Ardavin, Carlos, Cuenda, Ana
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396476/
https://ncbi.nlm.nih.gov/pubmed/22733747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207290109
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