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Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis

The immune response is normally controlled by regulatory T cells (Tregs). However, Treg deficits are found in autoimmune diseases, and therefore the induction of functional Tregs is considered a potential therapeutic approach for autoimmune disorders. The activation of the ligand-activated transcrip...

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Bibliographic Details
Main Authors: Yeste, Ada, Nadeau, Meghan, Burns, Evan J., Weiner, Howard L., Quintana, Francisco J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396465/
https://ncbi.nlm.nih.gov/pubmed/22745170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120611109
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