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Footprinting reveals that nogalamycin and actinomycin shuffle between DNA binding sites.
The hypothesis that sequence-selective DNA-binding antibiotics locate their preferred binding sites by a process involving migration from nonspecific sites has been tested by footprinting with DNAase I. Footprinting patterns on the tyrT DNA fragment produced by nogalamycin and actinomycin change wit...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1986
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC339639/ https://ncbi.nlm.nih.gov/pubmed/2421246 |
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