Maximum Diastolic Potential of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Depends Critically on I(Kr)

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) hold promise for therapeutic applications. To serve these functions, the hiPSC-CM must recapitulate the electrophysiologic properties of native adult cardiomyocytes. This study examines the electrophysiologic characteristics of hi...

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Detalhes bibliográficos
Main Authors: Doss, Michael Xavier, Di Diego, José M., Goodrow, Robert J., Wu, Yuesheng, Cordeiro, Jonathan M., Nesterenko, Vladislav V., Barajas-Martínez, Héctor, Hu, Dan, Urrutia, Janire, Desai, Mayurika, Treat, Jacqueline A., Sachinidis, Agapios, Antzelevitch, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396384/
https://ncbi.nlm.nih.gov/pubmed/22815737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040288
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