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Triplexator: Detecting nucleic acid triple helices in genomic and transcriptomic data

Double-stranded DNA is able to form triple-helical structures by accommodating a third nucleotide strand in its major groove. This sequence-specific process offers a potent mechanism for targeting genomic loci of interest that is of great value for biotechnological and gene-therapeutic applications....

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Autori principali: Buske, Fabian A., Bauer, Denis C., Mattick, John S., Bailey, Timothy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396377/
https://ncbi.nlm.nih.gov/pubmed/22550012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.130237.111
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